Used in research and development of vaccines and therapeutics targeting the Monkeypox virus. The L1R protein is a key target for neutralizing antibodies, making this recombinant protein valuable for immunogenicity studies and antibody detection assays. The mFc tag facilitates detection and purification, enabling efficient binding assays and protein interaction studies. Commonly employed in ELISA, Western blot, and immunization experiments to evaluate immune responses and screen monoclonal antibodies against Monkeypox.