Used in research and development for studying neurotrophic signaling pathways, particularly in neuronal survival, differentiation, and synaptic plasticity. Serves as a critical tool in assays evaluating ligand-receptor interactions involving neurotrophin-3 (NT-3). Employed in protein-protein interaction studies, ELISA, and surface plasmon resonance (SPR) due to the Fc tag enabling easy detection and immobilization. Supports drug discovery efforts targeting TrkC-related cancers and neurological disorders by acting as a soluble receptor for neutralization or binding studies. The Fc fusion enhances stability and solubility, making it suitable for in vitro and ex vivo applications.