Used in research and development for studying angiogenesis and vascular-related diseases. Plays a role in assays to evaluate inhibitors of VEGF signaling pathways, which are important in cancer and inflammatory conditions. Commonly employed in protein-protein interaction studies and as a capture or detection reagent in immunoassays due to the Fc tag facilitating purification and detection. Supports drug discovery efforts targeting receptor-ligand binding involved in tumor growth and metastasis.