Used in research and development of antibody-drug conjugates (ADCs) targeting TROP2-expressing cancers. Serves as an antigen for immunoassay development, antibody screening, and binding affinity studies, including ELISA and other binding assays. The His tag enables easy purification via nickel-affinity chromatography and detection in recombinant protein workflows. Commonly applied in cancer immunotherapy research, particularly for breast, lung, and pancreatic cancers.