Used in immunological research to study T cell regulation and immune responses. Serves as a biomarker and therapeutic target in autoimmune diseases and cancer immunotherapy. Employed in protein-protein interaction studies, ELISA, and antibody detection assays due to its tagged structure. Supports development of agonistic or antagonistic drugs targeting the GITR pathway. Commonly used in in vitro assays to modulate T regulatory cell activity and enhance effector T cell function.