Used in research to study immune regulation and apoptosis signaling pathways. Binds to TL1A (TNFSF15) and is employed in assays to investigate T cell activation, expansion, and differentiation, particularly in regulatory T cells and effector T cells. Applied in in vitro and in vivo models of autoimmune diseases, inflammation, and cancer immunotherapy to modulate immune responses. Also used as a detection tool in ELISA, flow cytometry, and protein interaction studies due to the Fc tag facilitating purification and detection. Supports development of therapeutic antibodies and evaluation of drug candidates targeting the DR3-TL1A axis.