Used in immunological research to study the TIGIT pathway, which plays a key role in regulating T cell and NK cell activity. Commonly applied in binding assays, protein-protein interaction studies, and immunoassays to evaluate interactions with ligands such as CD155 and CD112. Serves as a critical reagent in the development of immune checkpoint inhibitors for cancer immunotherapy. Also used in structural studies and antibody screening due to its functional Fc region, enabling detection and purification using standard secondary reagents.