Used in research to study neural development and axon guidance due to its role in regulating neurite outgrowth. Commonly employed in protein-protein interaction studies, especially in assays involving binding partners of SLITRK family receptors. The Fc tag enables easy detection and purification, making it suitable for ELISA, flow cytometry, and immunoprecipitation applications. Also utilized in structural and functional studies of synaptic formation and neurological disorders.