Used in immunological research to study cell signaling pathways involved in immune cell activation, particularly in natural killer (NK) cells and T cells. Serves as a target for therapeutic development in multiple myeloma and other hematological malignancies due to its high expression on malignant plasma cells. Employed in binding assays and drug screening to evaluate monoclonal antibodies and biologics, such as elotuzumab. Facilitates the development of immunoassays and flow cytometry protocols for detecting SLAMF7 expression in clinical and research settings. The His tag enables efficient purification and detection in recombinant protein applications.