Used in immunological research to study signal regulatory protein alpha (SIRPα) interactions, particularly in immune cell signaling and modulation. Plays a key role in investigating the CD47-SIRPα checkpoint pathway, which is involved in regulating phagocytosis and immune evasion, especially in cancer. Commonly employed in binding assays, protein-protein interaction studies, and as a detection tool in flow cytometry or ELISA. Also utilized in therapeutic development for targeting immune checkpoints in oncology and inflammatory diseases.