Used in research to study Wnt signaling pathway regulation. Helps in understanding cellular processes like development, differentiation, and cancer progression. Employed in protein-protein interaction studies and as a biomarker in disease models, particularly in metabolic and oncological conditions. Commonly utilized in ELISA, Western blot, and immunoprecipitation assays due to the His tag for detection and purification. Supports development of therapeutic strategies targeting Wnt-related diseases.