Used in research to study receptor tyrosine kinase signaling pathways involved in skeletal development and tissue morphogenesis. Facilitates protein-protein interaction studies due to the His tag, enabling easy purification and detection. Employed in binding assays to identify ligands or inhibitors targeting the ROR2 receptor. Supports development of therapeutic strategies for diseases linked to ROR2 dysfunction, such as brachydactyly type B and Robinow syndrome. Commonly used in ELISA, Western blotting, and pull-down assays in cell biology and drug discovery.