Used in research and diagnostic applications to study cell adhesion processes, particularly in inflammation and thrombosis. Binds to P-selectin glycoprotein ligand-1 (PSGL-1) and supports assays that investigate leukocyte rolling and endothelial interactions. Commonly employed in ELISA, flow cytometry, and protein-protein interaction studies. The Fc tag enables easy detection and purification, and facilitates dimerization for enhanced binding avidity. Also used in therapeutic development targeting cardiovascular diseases and immune disorders.