Used in research and development for studying platelet-derived growth factor receptor alpha (PDGFRA) signaling pathways involved in cell growth, proliferation, and survival. Commonly applied in immunoassays, protein-protein interaction studies, and receptor-ligand binding assays due to the His tag facilitating easy detection and purification. Supports development of targeted cancer therapies, especially in cancers with PDGFRA mutations such as gastrointestinal stromal tumors (GIST). Also utilized in diagnostic tool development and as a reference standard in Western blotting, ELISA, and flow cytometry. Enables evaluation of drug candidates targeting tyrosine kinase receptors.