Used in research to study prolactin signaling pathways involved in cell growth, differentiation, and survival. Commonly applied in immunoassays and protein-protein interaction studies due to the Fc tag, which allows detection and purification using anti-Fc antibodies. Supports development of therapeutic antibodies targeting the prolactin receptor, particularly in cancers where prolactin signaling is dysregulated, such as breast and prostate cancer. Also used as a capture molecule in ELISA and surface plasmon resonance (SPR) to measure binding affinity of ligands or inhibitors.