Used in research and development for studying cell signaling pathways involved in cell growth and division, particularly in connective tissue cells. Plays a role in assays to evaluate interactions with ligands or potential therapeutic agents targeting receptor tyrosine kinases. Commonly applied in protein-protein interaction studies, immunoassays, and as a control in Western blotting due to the Fc tag facilitating detection and purification. Supports drug discovery efforts in oncology and fibrotic diseases where PDGFRA signaling is implicated.