Used in research to study atherosclerosis and cardiovascular diseases by facilitating the investigation of oxidized low-density lipoprotein (oxLDL) uptake in endothelial cells. The His tag enables easy purification and detection, making it valuable in protein-protein interaction studies and screening potential therapeutic agents targeting LOX-1 pathways. Also employed in immunoassays and structural studies to understand the role of OLR1 in inflammation and plaque formation.