Used in immunological research to study cell adhesion and neural development due to its role in cell-cell interactions. Commonly employed in assays such as ELISA, flow cytometry, and protein-protein interaction studies to detect and quantify binding activity. The Fc tag enables easy detection and purification using anti-Fc antibodies or protein A/G systems. Valuable in cancer research, particularly for natural killer (NK) cell and neuroendocrine tumor studies, where CD56 expression is a key marker. Also utilized in therapeutic antibody development and target validation workflows.