Used in research to study neuromuscular junction formation and function, particularly in the context of autoimmune diseases like myasthenia gravis. The Fc tag enables easy detection and purification, making it valuable in immunoassays and protein interaction studies. Commonly employed in ELISA, Western blot, and flow cytometry to investigate antibody binding and receptor signaling. Also utilized in therapeutic development to evaluate potential inhibitors or modulators of MUSK activity.