Used in immunological research to study antigen presentation and dendritic cell function. Binds specifically to receptors involved in immune activation, making it valuable for developing targeted therapies, including cancer immunotherapies and vaccines. Commonly employed in flow cytometry, ELISA, and protein-protein interaction studies due to its high affinity and specificity. The Fc tag enables easy detection and purification, and supports use in therapeutic antibody development and immunoassay applications.