Human IL-7 with a His Tag is widely used in immunological research and therapeutic development. It plays a critical role in the development, survival, and homeostasis of T cells and B cells. The His Tag allows for easy purification and detection, making this protein ideal for in vitro studies involving lymphocyte proliferation and differentiation. It is commonly applied in cell culture systems to expand T cells, especially in cancer immunotherapy research, including CAR-T cell development. Researchers use it to maintain T cell viability and function during long-term cultures. It also supports the growth of hematopoietic stem cells and early lymphoid progenitors, making it valuable in studies of immune reconstitution, such as after bone marrow transplantation. Due to its role in enhancing immune responses, it is investigated in vaccine development and as an adjuvant in immunotherapies for chronic infections and immunodeficiency conditions. The His-tagged version ensures consistency and ease of handling in experimental setups, supporting reproducibility in preclinical studies.