Used in research and development for studying integrin-mediated cellular processes such as adhesion, migration, and signaling. Plays a role in investigating angiogenesis, tumor progression, and inflammatory diseases due to its involvement in extracellular matrix interactions. The Fc tag enables easy detection and purification, making it valuable in immunoassays, protein-protein interaction studies, and therapeutic target validation. Commonly used in ELISA, flow cytometry, and in vitro functional assays to block or activate integrin pathways.