Used in research to study cell signaling pathways related to growth and differentiation. Plays a role in immune regulation and inflammation studies. Applied in stem cell cultures to maintain pluripotency or direct differentiation. Utilized in cancer research to examine tumor progression and metastasis. Supports development of therapeutic proteins and biologics through protein-protein interaction studies. Employed in ELISA and Western blot as a detection standard due to the His tag. Enables purification via nickel-affinity chromatography in lab settings.