Used in research and development for studying interleukin-5 receptor signaling pathways involved in eosinophil activation and survival. Plays a role in immunological assays and binding studies to evaluate potential therapeutics for asthma, allergic inflammation, and other eosinophil-related disorders. Employed as a detection or capture reagent in ELISA and surface plasmon resonance due to its tagged Fc region. Supports the development of monoclonal antibodies targeting IL-5Rα by serving as a purified antigen in screening and characterization workflows.