Used in immunological research to study inflammation and immune responses. Helps in the development of therapies targeting autoimmune diseases, cancer, and chronic inflammatory conditions. The Fc tag enables easier detection and purification, and extends half-life in vivo, making it suitable for preclinical studies. Often employed in cell culture experiments to activate NK cells and induce IFN-γ production. Also used as a standard in immunoassays and for generating antibodies in animal models.