Used in immunological research to study the role of IL-13 signaling in inflammatory diseases such as asthma and allergic responses. The Fc tag enables easy detection and purification, making it valuable in binding assays and protein interaction studies. Frequently employed in ELISA, surface plasmon resonance, and flow cytometry to analyze receptor-ligand interactions. Also serves as a blocking agent to inhibit IL-13 activity in cell-based assays, helping to evaluate potential therapeutic targets. Widely applied in the development and validation of antibodies targeting the IL-13 pathway.