Used in cell culture and biopharmaceutical research to support the growth and differentiation of various cell types, especially in studies involving tissue regeneration, muscle development, and metabolic regulation. Frequently applied in stem cell cultures to enhance proliferation and maintain viability. Employed in protein-protein interaction studies due to the His tag, allowing easy purification and detection via affinity chromatography and immunoassays. Also utilized in diagnostic assays and therapeutic development for growth-related disorders.