Used in immunological research to study interleukin-13 signaling pathways involved in allergic responses and asthma. Serves as a capture antigen in ELISA and other immunoassays for detecting anti-IL-13 receptor antibodies or measuring receptor-ligand interactions. Employed in protein-protein interaction studies due to the His tag, enabling easy purification and detection. Supports development of therapeutic antibodies targeting IL-13 receptor for inflammatory diseases. Also used in cell binding assays to evaluate drug candidates that modulate IL-13 activity.