Used in research to study cell growth, differentiation, and survival due to its role in activating insulin-like growth factor receptors. Commonly applied in cell culture to support the growth of sensitive cell types, including stem cells and primary cells. Employed in protein-protein interaction studies owing to the Fc tag, which allows easy detection and purification using anti-Fc antibodies or protein A/G resins. Also utilized in therapeutic development for metabolic and degenerative diseases, leveraging its prolonged half-life in serum provided by the Fc fusion.