Used in research to study stem cell signaling pathways, particularly in the Wnt pathway, which plays a key role in tissue regeneration and cancer development. Helps in the development of targeted therapies by serving as a binding partner in protein interaction studies. Commonly used in immunoassays and protein purification due to the Fc tag, enabling easy detection and isolation. Supports drug discovery efforts focused on regenerative medicine and oncology by providing a tool to investigate LGR5-mediated cellular responses.