Used in immunological research to study myeloid cell signaling and immune regulation. Binds to DAMPs (damage-associated molecular patterns) and helps modulate inflammatory responses. Employed in protein-protein interaction studies, ELISA, and flow cytometry as a detection tool due to the His tag. Supports development of assays for monitoring myeloid-derived suppressor cells (MDSCs) in cancer and autoimmune diseases. Also used as an antigen for antibody development and in structural studies of C-type lectin receptors.