Used in research and development for studying macrophage biology and immune system regulation. Plays a key role in assays to evaluate receptor-ligand interactions, particularly in cancer and inflammatory disease studies. Commonly applied in ELISA, surface plasmon resonance, and binding studies to screen and characterize monoclonal antibodies or small molecule inhibitors targeting the CSF1R pathway. Also utilized in structural biology for protein purification and crystallography due to the His tag facilitating immobilization and detection.