Used in immunological research to stimulate the production and differentiation of granulocytes and macrophages from hematopoietic stem cells. Commonly applied in cell culture to support the growth of dendritic cells, which are critical for antigen presentation studies. Employed in cancer immunotherapy research to enhance immune responses by promoting the activation and expansion of antigen-presenting cells. Also utilized in the development and testing of monoclonal antibodies and other biologics targeting cytokine signaling pathways. The His tag facilitates easy purification and detection in experimental systems.