Used in research to study macrophage differentiation, survival, and activation. Supports the growth and maintenance of monocyte/macrophage lineage cells in cell culture. Employed in immunology studies to investigate roles of CSF1 in inflammation, tissue repair, and tumor-associated macrophages. The Fc tag enables easy detection and purification, and can be used in protein-protein interaction assays or for immobilization on Fc receptor-coated surfaces. Also utilized in therapeutic development targeting CSF1/CSF1R signaling pathways.