Used in immunological research to study T-cell activation and regulation. Binds to CD318 and ALCAM, making it valuable for investigating cell adhesion and immune synapse formation. Employed in protein binding assays and surface plasmon resonance to measure interaction kinetics. Serves as a detection tool in ELISA and flow cytometry due to the Fc tag enabling easy detection with anti-Fc antibodies. Supports development of therapeutic antibodies targeting immune disorders by blocking or modulating CD6-mediated signaling pathways.