Used in immunological research to study myeloid cell signaling and immune regulation. Binds to damage-associated molecular patterns (DAMPs) released by dead or stressed cells, helping investigate mechanisms of inflammation and immune tolerance. Employed in protein binding assays and surface plasmon resonance (SPR) to characterize interactions with ligands or therapeutic agents. Serves as a detection tool in flow cytometry and ELISA when paired with anti-Fc antibodies. Supports development of therapies targeting CLEC12A in hematological malignancies and autoimmune diseases.