Used in immunological research to study T cell activation and function. Binds specifically to MHC class I molecules, enabling investigation of immune responses. Employed in protein-protein interaction studies, immunoassays, and as a detection tool in flow cytometry and ELISA. Supports development of therapeutic antibodies and immune checkpoint inhibitors by providing a reliable reagent for characterizing CD8+ T cell behavior. Also utilized in structural studies to understand T cell receptor signaling mechanisms.