Human CD38, Fc Tag
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Recombinant Human CD38 protein with an Fc tag, used in immunological and molecular biology research to study the role of CD38 in the immune system. CD38 is a multifunctional ectoenzyme involved in T and B lymphocyte function, calcium signaling, and immune cell regulation. The Fc tag facilitates easy detection, purification, and dimerization for enhanced avidity in assays.
Commonly employed in functional assays, flow cytometry, ELISA, and protein-protein interaction studies to investigate CD38-mediated signaling pathways, including production of cADPR and ADP-ribose. Supports target validation for therapeutics targeting CD38-expressing cells, such as in multiple myeloma and other hematological malignancies. Widely applied in in vitro and in vivo models for cancer immunotherapy and immune response research, and serves as a standard or control in laboratory analyses.
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