Used in immunological research to study hematopoietic stem and progenitor cells. The His tag enables easy purification and detection, making it valuable in cell differentiation and stem cell therapy studies. Commonly used in flow cytometry, immunoassays, and protein-protein interaction experiments to isolate and characterize stem cell populations. Supports development of regenerative medicine and cancer research, particularly in leukemia where CD34 expression is a marker for certain cell types.