Used in immunological research to study the role of BTN3A1 (Butyrophilin subfamily 3 member A1) in γδ T cell activation. The Fc tag enables easy detection and purification, and supports binding assays to identify ligands or interacting partners. Commonly applied in protein-protein interaction studies, immunoassays, and flow cytometry. Also utilized in therapeutic development targeting immune regulation, particularly in cancer immunotherapy and infectious disease research.