Used in immunological research to study natural killer (NK) cell activation, this protein serves as a ligand for the NKp30 receptor. It helps in understanding immune responses against tumors and infected cells. Commonly applied in binding assays, protein-protein interaction studies, and immunoassay development. Also utilized in therapeutic antibody development and cancer immunotherapy research due to its role in modulating NK cell function. The Fc tag enables easy detection and purification, and supports use in cell-based assays and in vivo studies where prolonged half-life is beneficial.