Used in research to study lipid metabolism regulation, particularly in the development of therapies for hyperlipidemia and cardiovascular diseases. The His Tag allows for easy purification and detection, making it valuable in protein expression studies and binding assays. Investigated for its role in inhibiting lipoprotein lipase and endothelial lipase, thus influencing triglyceride and cholesterol levels. Potential target for monoclonal antibodies and RNA-based therapeutics aimed at reducing atherosclerotic risk.