Used in research to study ovarian reserve and follicular development in reproductive biology. Helps assess granulosa cell function and is applied in diagnostics for conditions like polycystic ovary syndrome (PCOS) and primary ovarian insufficiency. Employed in fertility testing to predict response to controlled ovarian stimulation in assisted reproductive technologies (ART). Also utilized in cancer research, particularly for granulosa cell tumors, as a biomarker for tumor presence and recurrence. The Fc tag enables detection and purification through antibody-based methods such as ELISA, flow cytometry, and protein purification systems.