Recombinant Human Fibronectin is widely used in cell culture applications, particularly in stem cell and regenerative medicine research. It serves as a critical extracellular matrix protein that supports cell adhesion, growth, migration, and differentiation. Because of its biocompatibility and functional similarity to natural fibronectin, it is used as a coating substrate for culturing sensitive cells such as induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs), helping maintain their undifferentiated state or guiding their differentiation into specific lineages. It is also employed in tissue engineering to enhance cell attachment to scaffolds and biomaterials. In therapeutic applications, recombinant fibronectin supports the expansion of hematopoietic stem cells for clinical use, including in bone marrow transplants and CAR-T cell manufacturing. Its recombinant origin ensures high purity, consistency, and reduced risk of pathogen contamination compared to plasma-derived fibronectin, making it ideal for GMP-compliant processes and advanced therapy development.