Used in immunological research to study T cell regulation and immune checkpoint pathways. Supports development of cancer immunotherapies by enabling in vitro and in vivo binding assays with ligands such as CD155. Facilitates pharmacokinetic and pharmacodynamic studies in non-human primate models due to species compatibility. Employed in protein-protein interaction studies, ELISA, and flow cytometry to detect and quantify target molecule expression. Aids in antibody screening and optimization for therapeutic candidates targeting the TIGIT pathway.