Used in immunological research to study melanocyte development and function in non-human primates. Plays a key role in vaccine development and safety testing, particularly in preclinical studies involving primate models. The His Tag allows for easy detection and purification, making it valuable in protein expression and immunoassay applications. Supports research in autoimmune diseases, vitiligo, and melanoma due to PMEL's involvement in melanin synthesis and antigen presentation.