Used in immunological and oncology research to study angiogenesis and cell signaling pathways. Supports the development of monoclonal antibodies and biosimilars by serving as a target antigen in assay development. Employed in protein-protein interaction studies due to its functional domains. Facilitates preclinical testing in non-human primate models, especially in evaluating therapeutic agents targeting PDGF and VEGF pathways. The His tag enables easy purification and detection in experimental workflows.