Used in immunological research to study the function of CD73 (an ecto-5'-nucleotidase) in immune regulation, particularly in the adenosine pathway that modulates inflammation and immune responses. The Fc tag enables easy detection and purification, and supports use in binding assays, protein-protein interaction studies, and in vitro functional assays. Commonly applied in the development and testing of therapeutic antibodies targeting the CD73 pathway in cancer immunotherapy and autoimmune diseases. Also used as a control protein in flow cytometry, ELISA, and surface plasmon resonance (SPR) experiments.