Used in research to study leptin receptor signaling pathways in non-human primate models, particularly in metabolic and obesity-related studies. The His Tag allows for easy purification and detection, making it valuable in protein expression and binding assays. Commonly applied in immunological and structural studies to understand receptor-ligand interactions and to develop therapeutic antibodies or drugs targeting the leptin pathway. Also utilized in comparative biology to assess cross-reactivity with human leptin receptors.