Used in immunological research to study T-cell development and regulation, particularly in non-human primate models. The Fc tag enables easy detection and purification, making it valuable for assays such as ELISA, flow cytometry, and immunoprecipitation. Plays a role in investigating immune responses, autoimmune diseases, and vaccine development due to its involvement in IL-7 signaling. Supports the development of therapeutic antibodies and biologics by serving as a target antigen in preclinical studies.